The clinical and genetic features of COPD-asthma overlap syndrome
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چکیده
منابع مشابه
The clinical and genetic features of COPD-asthma overlap syndrome.
Individuals with chronic obstructive pulmonary disease (COPD) and asthma are an important but poorly characterised group. The genetic determinants of COPD and asthma overlap have not been studied. The aim of this study was to identify clinical features and genetic risk factors for COPD and asthma overlap. Subjects were current or former smoking non-Hispanic whites or African-Americans with COPD...
متن کاملThe clinical features of the overlap between COPD and asthma
BACKGROUND The coexistence of COPD and asthma is widely recognized but has not been well described. This study characterizes clinical features, spirometry, and chest CT scans of smoking subjects with both COPD and asthma. METHODS We performed a cross-sectional study comparing subjects with COPD and asthma to subjects with COPD alone in the COPDGene Study. RESULTS 119 (13%) of 915 subjects w...
متن کاملThe Asthma-COPD Overlap Syndrome.
Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.
متن کاملThe Asthma-COPD Overlap Syndrome
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are pulmonary disorders characterized by various degrees of airflow limitation, inflammation and tissue remodeling. Bronchial asthma, an allergic disease that develops in childhood, is physiologically characterized by reversible airflow obstruction. It has an episodic course and a generally favorable prognosis, as it responds well to anti-...
متن کاملLongitudinal changes in clinical outcomes in older patients with asthma, COPD and asthma-COPD overlap syndrome.
BACKGROUND The progression of obstructive airway diseases (OADs) including asthma, chronic obstructive pulmonary disease (COPD) and asthma-COPD overlap syndrome in older adults is not well understood. OBJECTIVE To examine the prognosis of OADs and to identify potential determinants for longitudinal changes in clinical outcomes. METHODS We consecutively recruited 99 older adults (>55 years) ...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2014
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00216013